个人简介：

师伟伟，化学生物学系，廖茂富讲席教授课题组研究副教授，硕士生导师。

2014 年于中国科学技术大学获得理学博士学位， 2014-2018 期间在香港中文大学完成博士后研究工作，深圳市高层次海外人才。2019年3月获得广东省自然科学研究系列副高级研究员职称。长期从事蛋白质结构、功能与分子机制研究，具有扎实的分子生物、生物化学和结构生物学的前沿实验技术和丰富的研究经验。

研究领域： 

1. 新型药物靶点蛋白的致病分子机制研究

2. 基于结构与功能的新型药物发现和开发。

代表文章： 

1. Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC*. Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase. Int J Mol Sci. 2021 Oct 27;22(21):11598.

2. Shou JW, Cheung CK, Gao J, Shi WW*, Shaw PC*. Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation. Front Cell Neurosci. 2019 Sep 3;13:395.

3. Shi WW, Wong KB, Shaw PC*. Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein. Toxins. 2018 Aug 20;10(8):335.

4. Shi WW, Mak AN, Wong KB, Shaw PC*. Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins. Molecules. 2016 Nov 21;21(11):1588.

5. Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC*. Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2. Toxins (Basel). 2016 Oct 13;8(10):296.

6. Shi WW#, Jiang YL#, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H*, Chen Y*, Zhou CZ*. Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins. J Biol Chem. 2014 Jul 25;289(30):20898-907.

Du Y#, Shi WW#, He YX, Yang YH, Zhou CZ* and Chen Y*. Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC. Biochem J. 2011; 436:283-9.