李鹏飞，博士，长聘副教授（研究员），博士生导师。深圳市海外高层次“孔雀计划”人才（B类），深圳市“后备级”人才。现任校纪委委员，理学院党委委员，化学系党委副书记、副主任。曾任深圳市南山区第四、五届政协委员，校党委委员，化学系党支部、党总支书记。于2009年中国科学院大连化学物理研究所获有机化学博士学位，师从梁鑫淼研究员。2009-2011年先后在香港理工大学、香港浸会大学从事博士后研究工作，师从陈新滋院士。2012年起任南方科技大学化学系助理教授（副研究员），组建有机仿生催化课题组，独立开展研究工作。2019年8月晋升为长聘副教授（研究员）。该课题组致力于：1）不对称催化研究领域：远程立体控制实现立体中心的高效构建、新型有机催化剂的研发及应用、高附加值化学品的策略合成；2）化学生物学：多功能探针的研发、蛋白标记技术、磷酸化蛋白标准品的开发等研究方向。至今在JACS、ACIE、PNAS等期刊上发表论文90余篇，曾主持国家自然科学基金委、深圳市科技创新委员会等多个项目。

工作及教育背景

2019.08-今            南方科技大学化学系，副教授（研究员）
2012.01-2019.07 南方科技大学化学系，助理教授（副研究员）
2011.07-2011.12 香港浸会大学创意研究院，博士后研究员
导师：陈新滋（Albert S C Chan）院士
2009.07-2011.07 香港理工大学应用生物及化学科技学系，助理研究员
导师：陈新滋（Albert S C Chan）院士
2006.09-2009.07 中国科学院大连化学物理研究所，有机化学 博士
导师：梁鑫淼 研究员
2003.09-2006.07 大连理工大学化工学院，应用化学 硕士
导师：李宗石 教授
1999.09-2003.07 青岛大学化工学院，化学工程与工艺 学士

所获荣誉

2024年获校优秀党务工作者

2023年获校优秀共产党员、树德书院优秀导师、校优秀员工

2022年获树德书院优秀导师

2021年获校十佳优秀党务工作者、校优秀员工

2020年获校优秀党务工作者、校优秀工会工作者、校优秀员工

2019年获校优秀党务工作者、校优秀员工

2018年获校优秀青年科研奖、校优秀共产党员、校优秀工会干部、校五年服务奖

2017年获校优秀党务工作者、校招生工作先进个人

2016年获中共深圳市委教育工委系统优秀党务工作者、校优秀书院导师、  校优秀服务奖

2015年获校招生工作先进个人

2012年获校优秀员工

发表论文

2024

1. Tao Wang,† Zhongyue Lu,† Pengfei Li*. Catalyst-free reaction of 2-(4H-benzo[d][1,3]oxazin-4-yl)acrylates: synthesis of 1,2-dihydroquinolines and 2,3-dihydropyrroles. Chem. Commun., 2024, 60, 6933-6936.

2. Yuncong Lei, Xuling Chen, Yantong Jiang, Pengfei Li*. Phosphine-catalyzed asymmetric allylic alkylation of isoxazol-5(4H)-ones with Morita-Baylis-Hillman carbonates. Current Organocatalysis, 2024, BMS-COCAT-2024-3.

3. Tingting Huang, Chenxiao Qian, Pengfei Li*. Organocatalytic Csp2-O amination of quinolin-4(1H)-ones with 3-alkynyl-3-hydroxyisoindolinones. J. Org. Chem., 2024, 89, 9086-9091.

4. Xing Wang,† Boming Shen,† Meiwen Liu,† Ziyang Wang, Chang Liu, Pengfei Li*, Peiyuan Yu*, Wenjun Li*. Organocatalytic enantioselective 1,12-addition of alkynyl biphenyl quinone methides formed in situ. Angew. Chem. Int. Ed., 2024, e202400143.

(Highlighted by X-MOL https://www.x-mol.com/news/888019;

https://mp.weixin.qq.com/s/brjers9lNdf4ITWiJLVRGQ)

5. Zhenxiang Zheng, Ya Zeng, Kunjia Lai, Bin Liao, Pengfei Li and Chris Soon Heng Tan*. Protein painting for structural and binding site analysis via intracellular lysine reactivity profiling with o-phthalaldehyde. Chem. Sci., 2024, 15, 6064-6075.

6. Xing Guo,† Yan Chu Cheung,† Can Li, Han Liu,* Pengfei Li*, Sheng Chen,* Xuechen Li*. Investigation on the substrate specificity and N-substitution tolerance of PseF in catalytic transformation of pseudaminic acids to CMP-Pse derivatives. Chem. Sci., 2024, 15, 5950-5956.

7. Chenxiao Qian,† Jing Huang,† Tingting Huang,† Lijuan Song, Jianwei Sun,* Pengfei Li*. Organocatalytic enantioselective synthesis of Csp2–N atropisomers via formal Csp2–O bond amination. Chem. Sci., 2024, 15, 3893-3900.

(Highlighted by X-MOL https://www.x-mol.com/news/880841;

https://mp.weixin.qq.com/s/cQn3Jql52sZ26IcAeWDDoQ; 

RSC英国皇家化学会https://mp.weixin.qq.com/s/a9do1bOH5Qj5eeECjJrGtw)

8. Lunfeng Chen, Pengfei Li.* Enantioselective synthesis of 3-allylindoles from indolin-2-imines and MBH carbonates via nucleophilic catalysis. ChemistrySelect, 2024, 9, e202304866.

9. Zhibin Yue,† Yan Xia,† Boming Shen, Chang Liu, Peiyuan Yu, Pengfei Li,* Wenjun Li.* Organocatalytic remote stereocontrolled synthesis of tetrasubstituted allenes via asymmetric 1,8-addition of propargylic aza-p-quinone methide. Adv. Synth. Catal., 2024, 366, 1078–1083.

2023

10. Zhongyue Lu, Xuling Chen, Pengfei Li.* Organocatalytic regio- and enantioselective (3+3)-annulation of 2-(4H-benzo[d][1,3]oxazin-4-yl)acrylates with 2,4-dihydro-3H-pyrazol-3-ones. Tetrahedron Chem, 2023, 8, 100048.

11. Meiwen Liu,† Boming Shen,† Chang Liu, Peiyuan Yu,* Pengfei Li.* Organocatalytic enantioselective 1,8-addition for the synthesis of chiral tetraarylmethanes from 2-naphthol/naphthalen-2-amine-based tertiary alcohols. J. Am. Chem. Soc., 2023, 145, 14562–14569.

(Highlighted by X-MOL https://www.x-mol.com/news/857297; 

催化计https://mp.weixin.qq.com/s/_HO2yIKYQGnOfwskzPb_gg; 

化学谷https://mp.weixin.qq.com/s/D4e42E8l-bA4x3yPkt7eTw)

12. Zhibin Yue,† Boming Shen,† Jie Cao,† Xuling Chen, Fang Fang, Pengfei Li,* Peiyuan Yu,* Wenjun Li.* Organocatalytic enantioselective reaction of tertiary α-(7-indolyl)methanols with tryptamines. Org. Chem. Front., 2023, 10, 3662–3668.

13. Xing Guo, Pengfei Li, Han Liu,* Xuechen Li.* Recent progress on the chemical synthesis of bacterial non-2-ulosonic acids. Org. Chem. Front., 2023, 10, 3429–3446.

14. Zhibin Yue, Fang Fang, Yan, Xia, Pengfei Li,* Wenjun Li.* Organocatalytic remote stereocontrolled additions of in situ formed electron-deficient conjugate systems. Adv. Synth. Catal., 2023, 365, 1926–1933.

15. Xuling Chen, Pengfei Li.* Organocatalytic (1+4)-annulations of MBH adducts with electron-deficient systems. Chem. Rec., 2023, e202300152.

16. Chang Liu, Zhiyang Li, Pengfei Li,* Jianwei Sun.* Chiral phosphoric acid catalyzed redox deracemization of triarylmethanes. Chem. Synth., 2023, 3, 22.

17. Chang Liu, Jianwei Sun,* Pengfei Li.* Chiral phosphine catalyzed allylic alkylation of benzylidene succinimides with Morita-Baylis-Hillman carbonates. Molecules, 2023, 28, 2825.

18. Tao Wang, Boming Shen, Xuling Chen, Qianran Wan, Peiyuan Yu, Pengfei Li.* Organocatalytic regio- and enantioselective formal [4 + 2]-annulation of chiral nitrogen-containing dipoles. Chem. Synth., 2023, 3, 9.

19. Lunfeng Chen, Pengfei Li.* Organocatalytic regio- and enantioselective allylic alkylation of Indolin-2-imines with MBH carbonates towards 3-allylindoles. J. Org. Chem., 2023, 88, 7810–7814.

20. Xing Guo,† Boming Shen,† Chang Liu, Hongyue Zhao, Xuechen Li,* Peiyuan Yu,* Pengfei Li.* Rational design and organocatalytic enantioselective [1+4]-annulations of MBH carbonates with modified enones. Org. Chem. Front., 2023, 10, 150–156.

21. Yan Xia,† Meiwen Liu,† Chenxiao Qian, Pengfei Li,* Mingxin Dong,* Wenjun Li.* Asymmetric organocatalytic (3+2) annulation of propargylic alcohols with indolylnaphthalenols: synergistic construction of axial and central chirality. Org. Chem. Front., 2023, 10, 30–34.

2022

22. Qian Kong,† Mi Ke,† Yicheng Weng, Yunqiu Qin, An He, Pengfei Li,* Zongwei Cai,* Ruijun Tian.* Dynamic phosphotyrosine-dependent signaling profiling in living cells by two-dimensional proximity proteomics. J. Proteome Res., 2022, 21, 2727–2735.

23. Qian Kong,† Yicheng Weng,† Zhendong Zheng, Wendong Chen, Pengfei Li,* Zongwei Cai,* Ruijun Tian.* Integrated and high-throughput approach for sensitive analysis of tyrosine phosphoproteome. Anal. Chem., 2022, 94, 13728–13736.

24. Chenxiao Qian, Tingting Huang, Jianwei Sun,* Pengfei Li.* Catalyst-controlled divergent reactions of 2,3-disubstituted indoles with propargylic alcohols: synthesis of 3H-benzo[b]azepines and axially chiral tetrasubstituted allenes. Org. Lett., 2022, 24, 6472–6476.

 (Highlighted by ChemBeanGo, https://mp.weixin.qq.com/s/EfIm3RwLc_4HmGK6lmJbeQ)

25. Ziyang Wang,† Yuyu Cheng,† Zhibin Yue,† Xuling Chen, Pengfei Li,* Wenjun Li.* Organocatalytic asymmetric 3-allenylation of indoles via remote stereocontrolled 1,10-additions of alkynyl indole imine methides. Asian J. Org. Chem., 2022, 11, e202200399.

26. Zhibin Yue,† Ziyang Wang,† Yunfeng Zhang, Xuling Chen, Pengfei Li,* Wenjun Li.* Organocatalytic formal [3+3] cyclization of α-(6-indolyl) propargylic alcohols. Org. Biomol. Chem., 2022, 20, 6334–6338.

27. Tao Wang, Xuling Chen, Pengfei Li.* One-pot divergent synthesis of benzoxazines and dihydroquinolines from Morita-Baylis-Hillman alcohols. Eur. J. Org. Chem., 2022, e202200767. (Special Collection: Chinese YoungJOC, https://mp.weixin.qq.com/s/L8stts1docXoBFUzNYDpww )

28. Xiao Lin,† Boming Shen,† Ziyang Wang,† Yuyu Cheng, Xuling Chen, Pengfei Li,* Peiyuan Yu,* and Wenjun Li.* Organocatalytic enantioselective 1,10-addition of alkynyl indole imine methides with thiazolones: an access to axially chiral tetrasubstituted allenes. Org. Lett., 2022, 24, 4914–4918.

29. Xuling Chen, Tao Wang, Zhongyue Lu, Pengfei Li.* Organocatalytic enantioselective formal (4+2)-cycloadditions of phosphine-containing dipoles with isocyanates. Org. Lett., 2022, 24, 3102–3106.

30. Xing Wang, Xuling Chen, Wei Lin, Pengfei Li,* Wenjun Li.* Recent advances in organocatalytic enantioselective synthesis of axially chiral allenes. Adv. Synth. Catal., 2022, 364, 1212–1222. (VIP)

31. Xing Wang,† Qianqian Song,† Xuling Chen, Pengfei Li,* Yunkun Qi,* Wenjun Li.* Organocatalytic regio- and enantioselective aza-1,8-conjugate additions of isoxazol-5(4H) -ones to 6-methide-6H-indoles. Chin. J. Org. Chem., 2022, 42, 1722–1734.

32. Zhongyue Lu,† Yanwen Jia,† Xuling Chen, Pengfei Li.* Organocatalytic regio- and enantioselective [3+2]-annulations of ninhydrin-derived Morita-Baylis-Hillman carbonates with 3-methyleneoxindoles. J. Org. Chem., 2022, 87, 3184–3194.

33. Chenxiao Qian, Meiwen Liu, Jianwei Sun,* Pengfei Li.* Chiral phosphoric acid-catalyzed regio- and enantioselective reactions of functionalized propargylic alcohols. Org. Chem. Front., 2022, 9, 1234–1240.

34. Yu Wu,† Zhibin Yue,† Chenxiao Qian,† Xuling Chen, Fushuai Li, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective construction of axially chiral tetrasubstituted allenes via 1,6-addition of alkynyl indole imine methides with 2-substituted indoles. Asian J. Org. Chem., 2022, 11, e202100724.

35. Xiong Chen,† Shanping Ji,† Zheyi Liu,† Xiao Yuan, Congsheng Xu, Ruxi Qi, An He, Heng Zhao, Haiping Song, Chunlei Xiao, Weina Gao, Peng R. Chen, Ray Luo, Pengfei Li,* Fangjun Wang,* Xueming Yang, Ruijun Tian.* Motif-dependent immune co-receptor interactome profiling by photoaffinity chemical proteomics. Cell Chem. Biol., 2022, 29, 1024–1036. 

2021

36. Meiwen Liu, Chenxiao Qian, Pengfei Li.* Organocatalytic regio- and enantioselective N-alkylation of isoxazol-5-ones. Eur. J. Org. Chem., 2021, 48, 6777-6780. (e202101415)

37. Xiao Lin,† Keli Ge,† Ningning He,† Xuling Chen, Pengfei Li,* Mingxin Donga,* Wenjun Li.* Organocatalytic enantioselective construction of acyclic N,N-acetals via aza-addition of arylamines to ketimines. Adv. Synth. Catal., 2021, 363, 4332–4337.

38. Ziyang Wang,† Xiao Lin,† Xuling Chen,† Pengfei Li,* Wenjun Li.* Organocatalytic stereoselective 1,6-addition of thiolacetic acids to alkynyl indole imine methides: access to axially chiral sulfur-containing tetrasubstituted allenes. Org. Chem. Front., 2021, 8, 3469–3474.

39. Fushuai Li,† Zhihong Yang,† Yanyan Yang,† Qiuhong Huang, Xuling Chen, Pengfei Li,* Mingxin Dong,* Wenjun Li.* Organocatalytic enantioselective aza-Michael addition of arylamines to 7-methide-7H-indoles. Adv. Synth. Catal., 2021, 363, 2557–2561.

40. Xing Guo, Xuling Chen, Yuyu Cheng, Xiaoyong Chang, Xuechen Li,* Pengfei Li.* Organocatalytic enantioselective [2+4]-annulation of γ-substituted allenoates with N-acyldiazenes for synthesis of optically active 1,3,4-oxadiazines. Org. Biomol. Chem., 2021, 19, 1727–1731.

41. Fushuai Li,† Shuai Liang,† Yepeng Luan,† Xuling Chen, Hanhui Zhao, Anqi Huang, Pengfei Li,* Wenjun Li.* Organocatalytic regio-, diastereo- and enantioselective γ-additions of isoxazol-5(4H)-ones to β,γ-alkynyl-a-imino esters for synthesis of axially chiral tetrasubstituted a-amino allenoates. Org. Chem. Front., 2021, 8, 1243–1248.

42. Chenxiao Qian, Pengfei Li,* Jianwei Sun.* Catalytic enantioselective synthesis of spirooxindoles by oxidative rearrangement of indoles. Angew. Chem. Int. Ed., 2021, 60, 5871–5875. (Highlighted by X-MOL, https://www.x-mol.com/news/513116; Chem-station, https://cn.chem-station.com/化学杂记/recentpaper/2021/01/香港科技大学孙建伟与南方科技大学李鹏飞课题组an.html).

2020

43. Qianqian Song,† Pei Zhang,† Shuai Liang,† Xuling Chen, Pengfei Li,* Wenjun Li.* Organocatalytic regio- and enantioselective 1,8-additions of nitrogen and sulfur nucleophiles to 6-methylene-6H-indoles. Org. Lett., 2020, 22, 7859–7863. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/53275).

44. Fushuai Li,† Xuling Chen,† Shuai Liang, Zhenyan Shi, Pengfei Li,* Wenjun Li.* Organocatalytic site- and stereoselective 1,6-additions of N-aryl-3-oxobutanamides to propargylic aza-p-quinone methides. Org. Chem. Front., 2020, 7, 3446–3451.

45. Ziyang Wang,† Anqi Huang,† Fang Fang, Pengfei Li,* Guokai Liu,* Wenjun Li.* Non-hydrogen bond catalyst mediated diastereoselective conjugate addition of 5H-oxazol-4-ones to o-hydroxyphenyl substituted p-quinone methides. Org. Biomol. Chem., 2020, 18, 6807–6811.

46. Anqi Huang, Xing Guo, Pengfei Li,* Wenjun Li.* Recent advances in catalytic asymmetric reactions of thiazolones, rhodanines and their derivatives. Adv. Synth. Catal., 2020, 362, 3542–3557. (Very Important Publication)

47. Qian Kong,† Peiwu Huang,† Bizhu Chu, Mi Ke, Wendong Chen, Zhendong Zheng, Shanping Ji, Zongwei Cai,* Pengfei Li,* Ruijun Tian.* High-throughput and integrated chemical proteomic approach for profiling phosphotyrosine signaling complexes. Anal. Chem., 2020, 92, 8933–8942.

48. Xiao Lin,† Fang Fang,† Wei Lin, Zhantao Liu, Xiaoyong Chang, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective α-amination via conjugate addition of 5H-thiazol-4-ones to arylazocarboxylates: access to chiral N,S-acetals. Asian J. Org. Chem., 2020, 9, 1187–1191.

49. Fushuai Li,† Chen Zhang,† Yuyu Cheng,† Qianfa Jia, Wenjun Li, Kun Liu,* Pengfei Li.* Enantioselective construction of vicinal sulfur-functionalized quaternary and tertiary stereocenters via organocatalytic Michael addition of 5H-thiazol-4-ones to 1-azadienes. Asian J. Org. Chem., 2020, 9, 1183–1186.

50. Chang Liu, Pengfei Zhang, Pengfei Li.* Asymmetric organocatalytic enantioselective [1+4]-annulation of Morita-Baylis-Hillman carbonates with thiazolyl enones for assembling of dihydrofurans featuring thiazole skeleton. Chem. J. Chin. Univ., 2020, 10, 2272–2278.

51. Yuyu Cheng, Zhongyue Lu, Pengfei Li.* Organocatalytic regioselective [3+2] annulation of Morita-Baylis-Hillman carbonates with azonaphthalenes: an efficient access to 3-spiropyrazole-2-oxindoles. Current Organocatalysis, 2020, 7, 134–139.

52. Hongtian Liu, Juewei Ning, Guangjie Song, Xiangzhong Sun, Fengyu Su,* Pengfei Li,* Yanqing Tian.* Tricolor dual sensor for ratiometrically analyzing potassium ions and dissolved oxygen. Spectrochim. Acta Part A: Mol. Biomol. Spectrosc., 2020, 232, 118155.

53. Chen Zhang,† Yuyu Cheng,† Fushuai Li,† Yepeng Luan, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective regiodivergent C-H bond functionalization of 1-naphthols with 1-azadienes. Adv. Synth. Catal., 2020, 362, 1286–1291.

2019

54. Lili Zhang,† Yuzhe Han,† Anqi Huang, Pei Zhang, Pengfei Li,* Wenjun Li.* Organocatalytic remote stereocontrolled 1,8-additions of thiazolones to propargylic aza-p-quinone methides. Org. Lett., 2019, 21, 7415–7419. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)

55. Chen Zhang,† Xinye Shang,† Yuyu Cheng,† Fushuai Li, Hanhui Zhao, Pengfei Li,* Wenjun Li.* Enantioselective construction of 3-substituted 3-amino-2-oxindoles containing an N,N-ketal skeleton via organocatalyzed aza-addition of isatin imines. Org. Biomol. Chem., 2019, 17, 8374–8378.

56. Yuyu Cheng, Zhiqiang Fang, Yanwen Jia, Zhongyue Lu, Wenjun Li,* Pengfei Li.* Organocatalytic enantioselective conjugate addition of 2-naphthols to ortho-hydroxyphenyl substituted para-quinone methides: access to unsymmetrical triarylmethanes. RSC Adv., 2019, 9, 24212–24217.

57. Yipeng Luan,† Anqi Huang,† Yuyu Cheng, Xiaohong Liu, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective Michael addition of oxazolones to 2-enoylpyridine N-oxides for assembling of pyridine N-oxides featuring vicinal oxygen-containing tetrasubstituted stereocenters. Adv. Synth. Catal., 2019, 361, 4208–4214.

58. Wei Lin, Xiao Lin, Yuyu Cheng, Xiaoyong Chang, San Zhou, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective direct vinylogous Michael addition of γ-substituted deconjugate butenolides to azadienes. Org. Chem. Front., 2019, 6, 2452–2456.

59. Pei Zhang,† Qiuhong Huang,† Yuyu Cheng, Rongshi Li,* Pengfei Li,* Wenjun Li.* Remote stereo-controlled construction of vicinal axially chiral tetrasubstituted allenes and heteroatom-functionalized quaternary carbon stereocenters. Org. Lett., 2019, 21, 503–507. (Highly Cited Paper, Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)

60. Pengfei Zhang, Xing Guo, Chang Liu, Wenjun Li,* Pengfei Li.* Enantioselective construction of pyridine N-oxides featuring 2,3-dihydrofuran motifs via phosphine catalyzed [4+1]-annulation of 2-enoylpyridine N-oxides with Morita-Baylis-Hillman carbonates. Org. Lett., 2019, 21, 152-155. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590) 

61. Chenxiao Qian,† Pangmiaomiao Zhang,† Wenjun Li,* Pengfei Li.* Phosphine catalyzed enantioselective [1 + 4]-annulation of Morita-Baylis-Hillman carbonates with α,β-unsaturated imines. Asian J. Org. Chem., 2019, 8, 242–245. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

62. Wei Lin, Chen Zhang, Wen Xu, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Organocatalytic asymmetric Michael addition of rhodanines to azadienes for assembling of sulfur-containing tetrasubstituted carbon stereocenters. Adv. Synth. Catal., 2019, 361, 476–480. 

2018

63. Tao Wang,† Pengfei Zhang,† Wenjun Li,* Pengfei Li.* Phosphine-mediated enantioselective [1+4]-annulation of Morita–Baylis–Hillman carbonates with 2-enoylpyridines. RSC Adv., 2018, 8, 41620–41623. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

64. Kun Liu, Xinye Shang, Yuyu Cheng, Xiaoyong Chang, Pengfei Li,* Wenjun Li.* Regioselective [3+2]-annulation of hydrazonyl chlorides with 1,3-dicarbonyl compounds for assembling of polysubstituted pyrazoles. Org. Biomol. Chem., 2018, 16, 7811–7814.

65. Qiuhong Huang, Yuyu Cheng, Huijun Yuan, Xiaoyong Chang, Pengfei Li,* Wenjun Li.* Organocatalytic enantioselective Mannich-type addition of 5H-thiazol-4-ones to isatin-derived Imines: access to 3-substituted 3-amino-2-oxindoles featured by vicinal sulfur-containing tetrasubstituted stereocenters. Org. Chem. Front., 2018, 5, 3226–3230. 

66. Fei Qi, Fang Fang, Pengfei Li.* Catalyst-free phospha-nucleophilic substitution of hydroxylactams by diarylphosphine oxide. Current Organocatalysis, 2018, 5, 145–149. 

67. Bizhu Chu,† An He,† Yeteng Tian, Wan He, Peizhong Chen, Jintao Hu, Ruilian Xu, Wenbin Zhou, Mingjie Zhang, Pengyuan Yang, Shawn S. C. Li, Ying Sun,* Pengfei Li,* Tony Hunter, Ruijun Tian.* Photoaffinity engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. Proc. Natl. Acad. Sci. USA, 2018, 115, E8863–E8872. (Highlighted by SUSTech News) 

68. Yuyu Cheng, Zhiqiang Fang, Wenjun Li,* Pengfei Li.* Phosphine-mediated enantioselective [4+1] annulations between ortho-quinone methides and Morita-Baylis-Hillman carbonates. Org. Chem. Front., 2018, 5, 2728–2733. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

69. Lili Zhang, Huijun Yuan, Wei Lin, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Catalyst-controlled diastereodivergent construction of vicinal sulfur-functionalized quaternary and tertiary stereocenters. Org. Lett., 2018, 20, 4970–4974.

70. Qiuhong Huang, Lili Zhang, Yuyu Cheng, Pengfei Li,* Wenjun Li.* Enantioselective construction of vicinal sulfur-containing tetrasubstituted stereocenters via organocatalyzed Mannich-type addition of rhodanines to isatin imines. Adv. Synth. Catal., 2018, 360, 3266–3270. 

71. Wenjun Li,* Xianhong Xu, Pengfei Zhang, Pengfei Li.* Recent advances in catalytic enantioselective reactions of para-quinone methides. Chem. Asian J., 2018, 13, 2350–2359. (Invited for the Special Issue on Homogeneous Catalysis from Young Investigators in Asia)

72. Wenjun Li,* Huijun Yuan, Zhantao Liu, Zhongyin Zhang, Yuyu Cheng, Pengfei Li.* NHC-catalyzed enantioselective [4 + 3] cycloaddition of ortho-hydroxyphenyl substituted para-quinone methides with isatin-derived enals. Adv. Synth. Catal., 2018, 360, 2460–2464. ( Highly Cited Paper, Web of Science, Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)

73. Wenjun Li,* Xianhong Xu, Yang Liu, Hua Gao, Yuyu Cheng, Pengfei Li.*  Enantioselective organocatalytic 1,6-addition of azlactones to para-quinone methides: an access to α,α-disubstituted and β,β-diaryl-α-amino acid esters. Org. Lett., 2018, 20, 1142–1145. ( Highly Cited Paper, Web of Science, Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/47606)

74. Xinye Shang, Kun Liu, Zhongyin Zhang, Xianhong Xu, Pengfei Li,* Wenjun Li.* Direct access to spirobiisoxazoline via double 1,3-dipolar cycloaddition of nitrile oxide with allenoate. Org. Biomol. Chem., 2018, 16, 895–898. 

2017

75. Yuzhe Han, Yingzu Zhu, Pangmiaomiao Zhang, Wenjun Li,* Pengfei Li.* A catalyst-free cycloaddition reaction: access to spiro[chroman-3,2’-indene-1’,3’-dione] scaffolds. Chemistryselect, 2017, 2, 11380–11383. 

76. Lili Zhang,† Xiao Zhou,† Pengfei Li, Zhantao Liu, Yang Liu, Yong Sun, Wenjun Li.* Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and β-functionalized ketone. RSC Adv., 2017, 7, 39216–39220. 

77. Yuyu Cheng,† Yuzhe Han,† Pengfei Li.* Organocatalytic enantioselective [1+4] annulation of Morita-Baylis-Hillman carbonates with electron-deficient olefins: access to chiral 2,3-dihydrofuran derivatives. Org. Lett., 2017, 19, 4774–4777. (Highlighted by ChemBeanGo, https://www.chembeango.com/zixun/35590)

78. Yuyu Cheng, Pengfei Zhang, Yanwen Jia, Zhiqiang Fang, Pengfei Li.* Organocatalytic condensation–ring opening–annulation cascade reactions between N-Bocindolin-2-ones/benzofuran-2(3H)-ones and salicylaldehydes for synthesis of 3-arylcoumarins. Org. Biomol. Chem., 2017, 15, 7505–7508. (Highlighted as Front Cover)

79. Lu Yu, Yuyu Cheng, Fei Qi, Rou Li, Pengfei Li.* Organocatalytic regioselective, diastereoselective, and enantioselective annulation of cyclic 1-azadiene with γ-nitro ketone via 3,4-cyclization. Org. Chem. Front., 2017, 4, 1336–1340. 

80. Jindian Duan, Yuyu Cheng, Jing Cheng, Rou Li, Pengfei Li.* Organocatalytic asymmetric benzylation and aldol-hemiacetalization of α,β-unsaturated trifluoromethyl ketones: efficient enantioselective construction of 3,4-dihydroisocoumarins. Chem. Eur. J., 2017, 23, 519–523. (Highlighted as Inside Front Cover)

2016

81. Fei Qi, Rou Li, Fang Fang, Pengfei Li.* Autocatalytic nucleophilic substitution of hydroxylactam by thiophenol: access to N(acyl),S-acetals. Current Green Chemistry, 2016, 3, 235–241.

82. Jindian Duan, Yuyu Cheng, Rou Li, Pengfei Li.* Synthesis of spiro[indane- 1,3-dione-1-pyrrolines] via copper-catalyzed heteroannulation of ketoxime acetates with 2-arylideneindane-1,3-diones. Org. Chem. Front., 2016, 3, 1614–1618. (Highlighted as Inside Front Cover) 

83. Lu Yu, Yuyu Cheng, Rou Li, Yanhua Jiao,* Pengfei Li.* Tandem cyclization reaction between optically active γ-nitro ketone and chalcone towards the synthesis of chiral cyclohexane skeletons bearing five stereocenters. Chin. J. Org. Chem., 2016, 36, 1572–1579. (Highlighted as Front Cover)

84. Jindian Duan, Jing Cheng, Yuyu Cheng, Pengfei Li.* Synthesis of dinitrogen-fused spiro heterocycles via organocatalytic 1,3-dipolar cycloaddition of 2-arylidene-1,3-indandiones and azomethine imines. Asian J. Org. Chem., 2016, 5, 477–480. 

85. Lu Yu, Zhen Yang, Jianzhao Peng, Pengfei Li.* Substrate-controlled synthesis of functionalized cyclohexanes with four stereocenters via organocatalytic asymmetric domino reaction between γ-nitro ketone and enone. Eur. J. Org. Chem., 2016, 535–540. 

86. Jindian Duan, Jing Cheng, Pengfei Li.* DBU catalyzed one-pot multicomponent reaction for the synthesis of spirocyclic tetrahydrothiophene derivatives. Current Organocatalysis, 2016, 3, 216–220.

2015

87. Jindian Duan, Jing Cheng, Bing Li, Fei Qi, Pengfei Li.* Enantioselective synthesis of spiro [1,3-indanedione-tetrahydrothiophene]s by organocatalytic sulfa-Michael/Michael domino reaction. Eur. J. Org. Chem., 2015, 6130–6134. 

88. Jindian Duan, Jing Cheng, Pengfei Li.* Enantioselective construction of spiro-1,3-indandiones with three stereocenters via organocatalytic Michael-aldol reaction of 2-arylideneindane-1,3-diones and nitro aldehydes. Org. Chem. Front., 2015, 2, 1048–1052. 

89. Fang Fang, Genghong Hua, Feng Shi,* Pengfei Li.* Organocatalytic enantioselective Friedel-Crafts reaction: an efficient access to chiral isoindolo-β-carboline derivatives. Org. Biomol. Chem., 2015, 13, 4395–4398. (Highlighted as Inside Front Cover)

90. Hongqi Tao, Jindian Duan, Qijie He, Jun Wang,* Pengfei Li.* Organocatalytic efficient synthesis of 3-substituted-3-hydroxy-indolin-2-one derivatives from isatins and 4-phenylbut-3-yn-2-one. Scientia Sinica Chimica, 2015, 45(4), 391–395.

2014

91. Lu Yu, Qingjing Yang, Pengfei Li.* Phase-transfer-catalyst-mediated domino reaction of γ-nitro ketones with chalcones: approach to functionalized six-membered-ring carbocycles. Eur. J. Org. Chem., 2014, 7499–7504.

92. Lu Yu, Pengfei Li.* New simple primary amine-thiourea organocatalysts and their application in asymmetric conjugate addition. Tetrahedron Lett., 2014, 55, 3697–3700.

93. Hongqi Tao, Jindian Duan, Pengfei Li.* Inorganic-base-catalysed synthesis of α, β- unsaturated ketones and 3,5-disubstituted cyclohex-2-en-1-ones. Asian J. Org. Chem., 2014, 3, 644–648.

94. Xin Yang, Jun Wang*, Pengfei Li.* Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons. Org. Biomol. Chem., 2014, 12, 2499–2513. (Highlighted as Front Cover)

95. Pengfei Li,* Fang Fang, Ji Chen, Jun Wang.* Organocatalytic asymmetric aza-Michael addition of pyrazole to chalcone. Tetrahedron: Asymmetry, 2014, 25, 98–101.

96. Jindian Duan, Pengfei Li.* Asymmetric organocatalysis mediated by primary amines derived from cinchona alkaloids: recent advances. Catal. Sci. Technol., 2014, 4, 311–320.

2013

97. Yinuo Wu, Fuk Yee Kwong, Pengfei Li,* Albert S C Chan.* An efficient oxidative cross-coupling reaction between C-H and N-H bonds; a transition-Metal-Free protocol at room temperature. Synlett, 2013, 24, 2009–2013. 

2012

98. Jun Wang, Pengfei Li,* Pui Ying Choy, Albert S C Chan,* Fuk Yee Kwong.* Recent advances and applications in organocatalytic asymmetric aza-Michael addition. ChemCatChem, 2012, 4, 917–925. (Invited, Highlighted as Back Cover)