个人简介

陈永龙，副教授，化学生物学系。西北师范大学学士和硕士，德国Essen大学博士。广东省特支计划“百千万工程领军人才”，深圳市高层次人才。研究项目获得多项国家自然科学基金委、科技部“973计划”、中国科学院“知识创新工程”重要方向项目以及深圳市科创委基础研究项目等的支持。已在PNAS、Nature Genetics、Cell Reports、Genes & Development、EMBO Journal 等期刊上发表论文60余篇。

研究领域

1. 脊椎动物早期发育的分子调控机制

2. 黑色素瘤转移的细胞和分子基础

教学

1. 模式生物和发育生物学-本科生

2. 再生生物学和再生医学-研究生

学术成果

1. Shi, Z., Liu, G., Jiang, H., Shi, S., Zhang, X., Deng, Y., and Chen, Y*. 2023. Activation of P53 pathway contributes to Xenopus hybrid inviability. Proc. Natl. Acad. Sci. U S A. 120(21):e2303698120. doi: 10.1073/pnas.2303698120.

2. Shi, Z., Xu, J., Niu, L., Shen, W., Yan, S., Tan, Y., Quan, X., Cheung, E., Huang, K*., Chen, Y*., Li, L*., and Hou, C*. 2023. Evolutionarily distinct and sperm-specific supersized chromatin loops are marked by Helitron transposons in Xenopus tropicalis. Cell Reports 42, 112151.

3. Niu, L., Shen, W., Shi, Z., Tan, Y., He, N., Wan, J., Sun, J., Zhang, Y., Huang, Y., Wang, W., Fang, C., Li, J., Zheng, P., Cheung, E*., Chen, Y*., Li, L*., Hou, C*. 2021. Three-dimensional folding dynamics of the Xenopus tropicalis genome. Nature Genetics 53, 1075-1087.

4. Zhao, H., Han, D., Dawid, I.B.*, Pieler, T.*, and Chen, Y*. 2012. Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. Proc. Natl. Acad. Sci. U S A. 109, 8594-8599.

5. Lei, Y., Guo, X., Liu, Y., Cao, Y., Deng, Y., Chen, X., Cheng, C.H.*, Dawid, I.B.*, Chen, Y*., Zhao, H*. 2012. Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc. Natl. Acad. Sci. U S A. 109, 17484-17489.