题名 | Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: Roles and mechanisms |
作者 | |
通讯作者 | Ni, Bing Jie |
发表日期 | 2022-10-01
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DOI | |
发表期刊 | |
ISSN | 0043-1354
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EISSN | 1879-2448
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卷号 | 224 |
摘要 | The global spread of antibiotic resistance genes (ARGs) has wreaked havoc with the treatment efficiency of antibiotics and, ultimately, anti-microbial chemotherapy, and has been conventionally attributed to the abuse and misuse of antibiotics. However, the ancient ARGs have alterative functions in bacterial physiology and thus they could be co-regulated by non-antibiotic conditions. Recent research has demonstrated that many non-antibiotic chemicals such as microplastics, metallic nanoparticles and non-antibiotic drugs, as well as some non-antibiotic conditions, can accelerate the dissemination of ARGs. These results suggested that the role of antibiotics might have been previously overestimated whereas the effects of non-antibiotic conditions were possibly ignored. Thus, in an attempt to fully understand the fate and behavior of ARGs in the eco-system, it is urgent to critically highlight the role and mechanisms of non-antibiotic chemicals and related environmental factors in the spread of ARGs. To this end, this timely review assessed the evolution of ARGs, especially its function alteration, summarized the non-antibiotic chemicals promoting the spread of ARGs, evaluated the non-antibiotic conditions related to ARG dissemination and analyzed the molecular mechanisms related to spread of ARGs induced by the non-antibiotic factors. Finally, this review then provided several critical perspectives for future research. |
关键词 | |
相关链接 | [Scopus记录] |
收录类别 | |
语种 | 英语
|
重要成果 | NI期刊
; ESI热点
|
学校署名 | 其他
|
资助项目 | Australian Research Council[DE220100530]
; Australian Research Council[DP220101139]
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WOS研究方向 | Engineering
; Environmental Sciences & Ecology
; Water Resources
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WOS类目 | Engineering, Environmental
; Environmental Sciences
; Water Resources
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WOS记录号 | WOS:000859403700009
|
出版者 | |
ESI学科分类 | ENVIRONMENT/ECOLOGY
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Scopus记录号 | 2-s2.0-85138830175
|
来源库 | Scopus
|
引用统计 |
被引频次[WOS]:67
|
成果类型 | 期刊论文 |
条目标识符 | http://kc.sustech.edu.cn/handle/2SGJ60CL/402667 |
专题 | 工学院_环境科学与工程学院 工学院 |
作者单位 | 1.Centre for Technology in Water and Wastewater,School of Civil and Environmental Engineering,University of Technology Sydney,Sydney,2007,Australia 2.School of Environmental Science and Engineering,College of Engineering,Southern University of Science and Technology,Shenzhen,518055,China |
推荐引用方式 GB/T 7714 |
Shi, Xingdong,Xia, Yu,Wei, Wei,et al. Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: Roles and mechanisms[J]. WATER RESEARCH,2022,224.
|
APA |
Shi, Xingdong,Xia, Yu,Wei, Wei,&Ni, Bing Jie.(2022).Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: Roles and mechanisms.WATER RESEARCH,224.
|
MLA |
Shi, Xingdong,et al."Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: Roles and mechanisms".WATER RESEARCH 224(2022).
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条目包含的文件 | 条目无相关文件。 |
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