题名 | Tough, self-healable and tissue-adhesive hydrogel with tunable multifunctionality |
作者 | |
通讯作者 | Ren, Fuzeng; Lu, Xiong |
发表日期 | 2017-04-14
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DOI | |
发表期刊 | |
ISSN | 1884-4049
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EISSN | 1884-4057
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卷号 | 9期号:4 |
摘要 | An ideal hydrogel for biomedical engineering should mimic the intrinsic properties of natural tissue, especially high toughness and self-healing ability, in order to withstand cyclic loading and repair skin and muscle damage. In addition, excellent cell affinity and tissue adhesiveness enable integration with the surrounding tissue after implantation. Inspired by the natural mussel adhesive mechanism, we designed a polydopamine-polyacrylamide (PDA-PAM) single network hydrogel by preventing the overoxidation of dopamine to maintain enough free catechol groups in the hydrogel. Therefore, the hydrogel possesses super stretchability, high toughness, stimuli-free self-healing ability, cell affinity and tissue adhesiveness. More remarkably, the current hydrogel can repeatedly be adhered on/stripped from a variety of surfaces for many cycles without loss of adhesion strength. Furthermore, the hydrogel can serve as an excellent platform to host various nano-building blocks, in which multiple functionalities are integrated to achieve versatile potential applications, such as magnetic and electrical therapies. |
相关链接 | [来源记录] |
收录类别 | |
语种 | 英语
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重要成果 | ESI高被引
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学校署名 | 通讯
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资助项目 | Sichuan Province Youth Science and Technology Innovation Team[2016TD0026]
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WOS研究方向 | Materials Science
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WOS类目 | Materials Science, Multidisciplinary
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WOS记录号 | WOS:000399409500001
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出版者 | |
EI入藏号 | 20171803634990
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EI主题词 | Tissue
; Tissue Engineering
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EI分类号 | Biomedical Engineering:461.1
; Biological Materials And Tissue Engineering:461.2
; Chemical Products Generally:804
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来源库 | Web of Science
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引用统计 |
被引频次[WOS]:443
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成果类型 | 期刊论文 |
条目标识符 | http://kc.sustech.edu.cn/handle/2SGJ60CL/28995 |
专题 | 工学院_材料科学与工程系 |
作者单位 | 1.Southwest Jiaotong Univ, Sch Mat Sci & Engn, Minist Educ, Key Lab Adv Technol Mat, Chengdu 610031, Sichuan, Peoples R China 2.Sichuan Univ, Genome Res Ctr Biomat, Natl Engn Res Ctr Biomat, Chengdu, Sichuan, Peoples R China 3.South China Univ Technol, Sch Mat Sci & Engn, Dept Polymer Sci & Engn, Guangzhou, Guangdong, Peoples R China 4.Southwest Univ Sci & Technol, Sch Mat Sci & Engn, Engn Res Ctr Biomass Mat, Minist Educ, Mianyang, Peoples R China 5.Flinders Univ S Australia, Ctr NanoScale Sci & Technol, Adelaide, SA, Australia 6.Flinders Univ S Australia, Sch Comp Sci Engn & Math, Adelaide, SA, Australia 7.Hong Kong Univ Sci & Technol, Dept Mech & Aerosp Engn, Hong Kong, Hong Kong, Peoples R China 8.Hong Kong Univ Sci & Technol, Dept Chem & Biomol Engn, Mat Characterisat & Preparat Facil, Hong Kong, Hong Kong, Peoples R China 9.Southwest Jiaotong Univ, Sch Mech & Engn, Chengdu, Sichuan, Peoples R China 10.South Univ Sci & Technol China, Dept Mat Sci & Engn, 1088 Xueyuan Blvd, Shenzhen 518055, Guangdong, Peoples R China |
通讯作者单位 | 材料科学与工程系 |
推荐引用方式 GB/T 7714 |
Han, Lu,Yan, Liwei,Wang, Kefeng,et al. Tough, self-healable and tissue-adhesive hydrogel with tunable multifunctionality[J]. NPG Asia Materials,2017,9(4).
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APA |
Han, Lu.,Yan, Liwei.,Wang, Kefeng.,Fang, Liming.,Zhang, Hongping.,...&Lu, Xiong.(2017).Tough, self-healable and tissue-adhesive hydrogel with tunable multifunctionality.NPG Asia Materials,9(4).
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MLA |
Han, Lu,et al."Tough, self-healable and tissue-adhesive hydrogel with tunable multifunctionality".NPG Asia Materials 9.4(2017).
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条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | 操作 | |
Han-2017-Tough, self(4574KB) | -- | -- | 开放获取 | -- | 浏览 |
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