Self-introduction

Yang Liang, professor of the School of Medicine Southern University of Science and Technology. Dr. Yang obtained his Bachelor’s degree in Biological Sciences from Nankai University in 2004, and Ph.D., from Technical University of Denmark in 2009. Dr. Yang joined the School of Biological Sciences, Nanyang Technological University, Singapore as Assistant Professor from 2012, and obtained tenure (Associate Professor) in 2018. Dr. Yang was nominated as Assistant Dean of the School of Biological Sciences, and Deputy Research Director of Public Health & Medical Biofilms in Singapore Centre for Environmental Life Sciences Engineering (SCELSE). Dr. Yang joined the School of Medicine, Southern University of Science and Technology as a full-time professor at the end of 2018. He was granted the Guangdong Outstanding Youth Fund, the Oversea High-Caliber Personnel (Level B) of Shenzhen.

Dr. Yang is currently in charge of 3 core teaching courses: "Medical Microbiology (Undergraduate)", "Medical Microbiology Experiment (Undergraduate)" and "Microbial Technology (Graduate)" at Southern University of Science and Technology.

Research Interests

Microbiology, infection, epidemiology, resistance gene transmission, biofilm, quorum sensing, drug development

Teaching

Lecturer: Medical Microbiology (Undergraduate)

Speaker: Medical Microbiology Experiment (Undergraduate)

Speaker: Microbial Technology (Graduate)

Educational Background

2000-2004 B.S., Nankai University

2004-2006 M.S., Danish Technical University

2006-2009 Ph.D., Technical University of Denmark

Professional experience

2009-2010 Postdoctoral, Danish Technical University

2011-2012 Postdoctoral, University of Hamburg (Germany)

2012 / 02-2012 / 06 Postdoctoral, Nanyang Technological University (Singapore)

2012 / 07-2018 / 02 Nanyang Technological University (Singapore) Assistant Professor

2018 / 03-2018 / 09 Nanyang Technological University (Singapore) Associate Professor

2018 / 10-present Professor of Southern University of Science and Technology

Honors & Awards

2007 American Microbiological Society Student Conference Travel Award

2010 Danish Medical Research Council Independent Postdoctoral Fund

2011 Humboldt Foundation Postdoctoral Scholarship, Germany

2011 FEMS Conference Young Scientist Travel Award

2012 Nanyang Assistant Professor Award, Singapore

2018 Tenure at Nanyang Technological University, Singapore

2019 Shenzhen Peacock Talent Class B

2019 Young Yangtze River Scholars

2020 Guangdong Outstanding Youth Fund

Professional Activities

2007-present: Member of American Society of Microbiology

2017-present: Member of International Society for Chemical Biology

2018-present: Editorial member of Biofilm (ISSN: 2590-2075).

2017- 2019: Editorial board member of Applied and Environmental Microbiology (Print ISSN: 0099-2240; Online ISSN: 1098-5336)

2015- 2016: Editorial Board of "New Horizons in Translational Medicine" (Official Journal of the European Society of Translational Medicine)

Microbiology, Environmental Microbiology, Environmental Microbiology Reports, Antimicrobial Agents and Chemotherapy, Medicinal Research Reviews, Applied and Environmental Microbiology, Journal of Antimicrobial Chemotherapy, Applied Microbiology and Biotechnology, PNAS, ISME J, Scientific Reports, BMC Microbiology, PLoS Pathogens, PLoS one, Reviewers in Trends in Biotechnology, Molecular Systems Biology, Current Opinion in Microbiology, Journal of Biochemistry, Chemical Communications, Water Research, ACS Chemical Biology, etc.

Selected Publication

1.Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles. NATURE COMMUNICATIONS 2014

2.In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm–dispersed cells via c-di-GMP manipulation. Nature Protocols 2015

3.Selective labelling and eradication of antibiotictolerant bacterial populations in Pseudomonas aeruginosa biofilms. NATURE COMMUNICATIONS 2016

4.A cyclic di-GMP-binding adaptor protein interacts with a chemotaxis methyltransferase to control flagellar motor switching. SCIENCE SIGNALING 2016

5.Ribosome protection by antibiotic resistance ATP-binding cassette protein. PNAS 2018

Journal Papers

The research team has trained more than 10 Ph.D. students and more than 10 Postdoctoral students. International academic journals include Lancet, Nature Communications, Science Signaling, Nature Protocols, Proc Natl Acad. Sci USA, Trends in Microbiology, mBio, Nano Letters, Current Opinion in Biotechnology, Briefings in Bioinformatics, Journal of Medicinal Chemistry, etc. Published more than 140 papers. The paper has been cited more than 8,000 times, H-Index 43 (Google Scholar). Professor Yang Liang has been invited to make academic reports more than 30 times in international academic conferences, universities and researches in the United States, Canada, Germany, Japan, Singapore and other countries.

Invention patent

1.Quorum Sensing Inhibitors. Sean Yang-Yi Tan, Liang Yang, Michael Givskov. US patent granted (US9988380B2)

2.Method Of Inhibiting Quorum Sensing In Pseudomonas Aeruginosa. Michael Christian Givskov, Shu Sin Chng, Liang Yang, Zhen Wei Leon Tan, Ziyan Hong. International patent filed (PCT/SG2016/050436)

3.Chemical Fluorescent Probes For Detecting Biofilms. Young-Tae Chang, Jun-Young Kim, Sahu SRIKANTA, Michael Christian Givskov, Liang Yang. International patent filed (US10416153B2)

Authored Books

1.Yang Liang, Wu Hong (2012). Microbial interactions and signal transmission in biofilms. "Microbial Biofilm and Infection", People's Medical Publishing House, ISBN-9787117156462

2.Yang Liang, Song Zhijun (2012). Multiple Species Bacterial Biofilms and Infection. "Microbial Biofilm and Infection", People's Medical Publishing House, ISBN-9787117156462

3.Chew SC, Yang L(2015) Biofilms. Encyclopedia of Food and Health. Elsevier, ISBN-9780123849533

4.den BestenH, Ding Y, Abee T, Yang L (2015) Emergent Strategies for Detection and Control of Biofilms in Food Processing Environments. Advances in Food Biotechnology. John Wiley & Sons, ISBN-9781118864555

5.Yang L, Chua SL (2017) Proteogenomics of Pseudomonas aeruginosain cystic fibrosis infections. MALDI-TOF and Tandem MS for Clinical Microbiology, John Wiley & Sons, ISBN: 9781118960257

6.Duang X, Fu Y, Yang L (2020). Molecular and Systems biology approaches for analyzing drug-tolerant bacterial persister cells. Mitigation of Antimicrobial Resistance, Springer Nature