Self-introduction

Dr. Fu Xuekun obtained Joint Ph.D. degree from Hong Kong Baptist University and Southern University of Science and Technology in 2020. Since 2022, Dr. Fu Xuekun was employed as Research Assistant Professor in Department of Biology, Southern University of Science and Technology. Dr. Fu Xuekun focuses on mechanistic studies   and translational medicine in bone & joint diseases and tumors.

Research Interests：

◆Mechanistic studies in bone & joint diseases and tumors;

◆Translational medicine in bone & joint diseases and tumors.

Selected Publication：

1. Fu X, Zhou B, Yan Q, Tao C, Qin L, Wu X, Lin S, Chen S, Lai Y, Zou X, Shao Z, Wang M, Chen D, Jin W, Song Y, Cao H, Zhang G, Xiao G. Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice. Signal Transduction and Targeted Therapy. 2020 Dec 26;5(1):297. doi: 10.1038/s41392-020-00328-y.

2. Fu X, Li Y, Huang T, Yu Z, Ma K, Yang M, Liu Q, Pan H, Wang H, Wang J, Guan M. Runx2/Osterix and Zinc Uptake Synergize to Orchestrate Osteogenic Differentiation and Citrate Containing Bone Apatite Formation. Advanced Science. 2018 Jan 28;5(4):1700755. doi: 10.1002/advs.

3. Lei Y, Fu X*, Li P, Lin S, Yan Q, Lai Y, Liu X, Wang Y, Bai X, Liu C, Chen D, Zou X, Cao X, Cao H, Xiao G. LIM domain proteins Pinch1/2 regulate chondrogenesis and bone mass in mice. Bone Research. 2020 Oct 13;8:37. doi: 10.1038/s41413-020-00108-y.

4. Qin L, Fu X*, Ma J, Lin M, Zhang P, Wang Y, Yan Q, Tao C, Liu W, Tang B, Chen D, Bai X, Cao H, Xiao G. Kindlin-2 mediates mechanotransduction in bone by regulating expression of Sclerostin in osteocytes. Communications Biology. 2021 Mar 25;4(1):402. doi: 10.1038/s42003-021-01950-4.

5. Li F, Wu X, Fu X*, Liu J, Song W, Xiao GG, Lu A, Zhang G. Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation. International Journal of Biological Sciences. 2022 Jan 9;18(3):1238-1253. doi: 10.7150/ijbs.58784.