Faculty

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Xiuxiu Li
Research Assistant Professor
Research Assistant Professor
lixx7@sustech.edu.cn

Educational background: 

2013.09 - 2018.06: Wuhan University, Organic Chemistry, Doctor of Science (Supervisor: Prof. Xumu Zhang)
2009.09 - 2013.06: Wuhan University, Chemistry Base Class, Bachelor of Science (Supervisor: Prof. Xumu Zhang )


Work experience: 

2023.06 – now: Southern University of Science and Technology,  Research Assistant Professor
2021.11 – 2023.06: Weizmann Institute of Science,  Postdoctoral Fellow
2018.07 − 2019.08: Southern University of Science and Technology, Visiting Scholar


Research Area:

Asymmetric catalysis: asymmetric hydrogenation; asymmetric hydroformylation; asymmetric hydroformylation tandem reaction etc.


Publications:

1. Shuailong Li,a Dequan Zhang,a Aiswarya Purushothaman, Hui Lv, Shilpa Shilpa, Raghavan B. Sunoj,* Xiuxiu Li* and Xumu Zhang*, Chemo-, Regio- and Enantioselective Hydroformylation of Trisubstituted Cyclopropenes: Access to Chiral Quaternary Cyclopropanes. Nat. Commun. 2024, 15, 6377. (a: contributed equally to this work) 

2. Xiuxiu Li, Polina Fomitskaya, Viktoryia A. Smaliak, Barbara S. Smith, Ekaterina V. Skorb and Sergey N. Semenov*, Selenium Catalysis Enables Negative Feedback Organic Oscillators. Nat. Commun. 2024, 15, 3316. 

3. Xiuxiu Li,a Cai You,a Jiaxin Yang, Shuailong Li, Dequan Zhang, Hui Lv* and Xumu Zhang*, Asymmetric Hydrocyanation of Alkenes without HCN. Angew. Chem. Int. Ed. 2019, 58, 10928-10931. (Cover Story, Hot Paper, Highlighted by ChemViews, Highlighted by Synfacts, 2019, 15, 1023) (a: contributed equally to this work) 

4. Cai You,a Xiuxiu Li,a Quan Gong, Jialin Wen* and Xumu Zhang*, Nickel-Catalyzed Desymmetric Hydrogenation of Cyclohexadienones: An Efficient Approach to All-Carbon Quaternary Stereocenters. J. Am. Chem. Soc. 2019, 141, 14560-14564. (a: contributed equally to this work) 

5. Cai You,a Xiuxiu Li,a Yuhong, Yang, Yusheng Yang, Xuefeng Tan, Shuailong Li, Biao Wei, Lung Wa Chung,* Hui Lv* and Xumu Zhang*, Silicon-Oriented Regio- and Enantioselective Rhodium-Catalyzed Hydroformylation. Nat. Commun. 2018, 9, 2045. (a: contributed equally to this work) 

6. Xiuxiu Li,a Cai You,a Yusheng Yang, Yuhong Yang, Pan Li, Guoxian Gu, Lung-Wa Chung, Hui Lv* and Xumu Zhang*, Rhodium-Catalyzed Asymmetric Hydrogenation of β-Cyanocinnamic Esters with the Assistance of a Single Hydrogen Bond in a Precise Position. Chem. Sci. 2018, 9, 1919-1924. (a: contributed equally to this work) 

7. Xiuxiu Li, Cai You, Shuailong Li, Hui Lv* and Xumu Zhang*, Nickel-Catalyzed Enantioselective Hydrogenation of β‑(Acylamino)acrylates: Synthesis of Chiral β‑Amino Acid Derivatives. Org. Lett. 2017, 19, 5130-5133. 

8. Xiuxiu Li, a Cai You, a Yusheng Yang, Fangyuan Wang, Shuailong Li, Hui Lv* and Xumu Zhang*, Rhodium-catalyzed Enantioselective Hydrogenation of α-Amino Acrylonitriles: An Efficient Approach to Synthesizing Chiral α-Amino Nitriles. Chem. Commun. 2017, 53, 1313-1316. (a: contributed equally to this work) 

9. Xiuxiu Li,a Cai You,a Hailong Yang, Jinteng Che, Pengyu Chen, Yusheng Yang, Hui Lv* and Xumu Zhang*, Rhodium-Catalyzed Asymmetric Hydrogenation of Tetrasubstituted Cyclic Enamides: Efficient Access to Chiral Cycloalkylamine Derivatives. Adv. Synth. Catal. 2017, 359, 597-602. (Highlighted by Synfacts, 2017, 13, 0292) (a: contributed equally to this work) 

10. Jiaxin Yang, Xiuxiu Li, Cai You, Shuailong Li, Yu-Qing Guan, Hui Lv* and Xumu Zhang, Rhodium-Catalyzed Asymmetric Hydrogenation of Exocyclic α,β-Unsaturated Carbonyl Compounds. Org. Biomol. Chem. 2020, 18, 856-859. 

11. Dequan Zhang, Cai You, Xiuxiu Li, Jialin Wen* and Xumu Zhang*, Asymmetric Linear-Selective Hydroformylation of 1,1-Dialkyl Olefins Assisted by a Steric-Auxiliary Strategy. Org. Lett. 2020, 22, 4523-4526. 

12. Shuailong Li, Zhuangxing Li, Cai You, Xiuxiu Li, Jiaxin Yang, Hui Lv* and Xumu Zhang*, Rhodium-Catalyzed Enantioselective Anti-Markovnikov Hydroformylation of α-Substituted Acryl Acid Derivatives. Org. Lett. 2020, 22, 1108-1112. 

13. Cai You, Shuailong Li, Xiuxiu Li, Hui Lv* and Xumu Zhang*, Enantioselective Rh-Catalyzed Anti-Markovnikov Hydroformylation of 1,1-Disubstituted Allylic Alcohols and Amines: An Efficient Route to Chiral Lactones and Lactams. ACS Catal. 2019, 9, 8529-8533. 

14. Yu-Qing Guan, Zhengyu Han, Xiuxiu Li, Cai You, Xuefeng Tan, Hui Lv* and Xumu Zhang, A Cheap Metal for a Challenging Task: Nickel Catalyzed Highly Diastereo- and Enantioselective Hydrogenation of Tetrasubstituted Fluorinated Enamides. Chem. Sci. 2019, 10, 252-256. 

15. Cai You, Shuailong Li, Xiuxiu Li, Jialing Lan, Yuhong Yang, Lung Wa Chung, Hui Lv* and Xumu Zhang*, Design and Application of Hybrid Phosphorus Ligands for Enantioselective Rh-Catalyzed Anti-Markovnikov Hydroformylation of Unfunctionalized 1,1-Disubstituted Alkenes. J. Am. Chem. Soc. 2018,140, 4977-4981. (Highlighted by Synfacts 2018, 14, 0602.) 

16. Weilong Wu, Yun Xie, Pan Li, Xiuxiu Li, Yuanhua Liu, Xiu-Qin Dong* and Xumu Zhang*, Asymmetric Hydrogenation of α-Hydroxy Ketones with an Iridium/f-Amphox Catalyst: Efficient Access to Chiral 1,2-Diols. Org. Chem. Front., 2017, 4, 555-559. 

17. Cai You, Biao Wei, Xiuxiu Li, Yusheng Yang, Yue Liu, Hui Lv* and Xumu Zhang*, Rhodium-Catalyzed Desymmetrization by Hydroformylation of Cyclopentenes: Synthesis of Chiral Carbocyclic Nucleosides.  Angew. Chem. Int. Ed. 2016, 55, 6511-6514. (Highlighted by Synfacts 2016, 12, 0822.) 


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