Dr. Guo received his B.S. from the Department of Mechanics at Peking University in 1984, M.S. in 1990 and Ph.D. in 1994 in Medical Engineering and Medical Physics from Harvard University-MIT. In 1994-1996, Professor Guo did his postdoctoral fellowship in the Orthopaedic Research Laboratories at the University of Michigan at Ann Arbor with Professor Steven A. Goldstein in orthopaedic bioengineering.In 1996 he joined the Department of Mechanical Engineering and then Department of Biomedical Engineering at Columbia University as an Assistant Professor.He was promoted to Associate Professor in 2001 and Associate Professor with tenure in 2003, and Professor in 2007. He directs the Bone Bioengineering Laboratory in the Department of Biomedical Engineering at Columbia focusing his research interests in micromechanics of bone tissue, computational biomechanics, and mechanobiology of bone.

His past honors include Young Investigator Recognition Award from the Orthopaedic Research Society, National Research Service Award from the US National Institutes of Health (NIH), a CAREER award from the US National Foundation of Science (NSF). He was elected as a fellow to the American Institute for Medical and Biological Engineering. He was one of the founders and served as co-Editor-in-Chief of Cellular and Molecular Bioengineering (CMBE), an international journal of US Biomedical Engineering Society (BMES). He has served many review panels for NIH, NSF, and NASA. His research has been supported by the Whitaker Foundation, the US NSF, and the NIH. He served as President of International Chinese Musculoskeletal Research Society, the Society for Physical Regulation in Biology and Medicine, Member of Board of Directors of Orthopaedic Research Society, and Member of Board of Directors of American Institute for Medical and Biological Engineering. He also founded the Special Interest Group (SIG) in CMBE in the BMES and served as its founding Chair.

Publications:

1.  Liu, X. S., Sajda, P., Saha, P. K.,Wehrli, F. W., Bevil, G., Keaveny, T. M., andGuo, X. E.(2008) Complete Volumetric Decomposition of IndividualTrabecular Plates and Rods and Its Morphological Correlations with AnisotropicElastic Moduli in Human Trabecular Bone, Journal of Bone Mineral Research,23(2):223-235.

2. Liu, X. S., Zhang, X. H., Sekhon, K.K., Admas, M. F., McMahon, D. J., Bilezikian, J. P., Shane, E., andGuo, X. E.(2010) High-ResolutionPeripheral Quantitative Tomography Can Assess Microstructural and MechanicalProperties of Human Distal Tibial Bone,Journalof Bone and Mineral Research,25(4):746–756.

3. Baik,A. D., Lu, X. L., Qiu, J., Huo, B., Hillman, E. M.C., Dong, C., andGuo, X. E.(2010) Quasi-3D CytoskeletalDynamics of Osteocytes under Fluid Flow, Biophysical Journal,99(9): 2812-2820.

4. Liu,X.S., Walker M.D., McMahon, D.J., Udesky, J., Liu, G., Bilezikian, J.P., andGuo, X. E.(2011) Better skeletalmicrostructure confers greater mechanical advantages in Chinese-American womenversus white women, Journal of Bone and Mineral Research,26(8):1783-1792.

5. Jing, D., Baik, A. D., Lu, X. L., Zhou, B., Lai, X.,Wang, L. Luo, E., andGuo, X. E.(2014) In Situ Intracellular CalciumOscillations in Osteocytes in Intact Mouse Long Bones under Dynamic MechanicalLoading,FASEB Journal,28(4):1582-1592.